DURABLE RESPONSE TO ANTI-PD-1 IMMUNOTHERAPY IN EPITHELIOID ANGIOMYOLIPOMA: A REPORT ON THE SUCCESSFUL TREATMENT OF A RARE MALIGNANCY

Durable response to anti-PD-1 immunotherapy in epithelioid angiomyolipoma: a report on the successful treatment of a rare malignancy

Abstract Background Malignant angiomyolipoma is an uncommon tumor of the class of perivasciular epithelioid cell neoplasms (PEComas).These tumors are characteristically driven by deleterious mutations in the tumor suppressors TSC1 and TSC2, whose gene products typically act to inhibit mTOR.There are several cases of malignant angiomyolipoma which e

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Quorum Quenching Properties and Probiotic Potentials of Intestinal Associated Bacteria in Asian Sea Bass Lates calcarifer

Vegetable Quorum quenching (QQ), the enzymatic degradation of N-acyl homoserine lactones (AHLs), has been suggested as a promising strategy to control bacterial diseases.In this study, 10 AHL-degrading bacteria isolated from the intestine of barramundi were identified by 16S rDNA sequencing.They were able to degrade both short and long-chain AHLs a

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Teens, screens and quarantine; the relationship between adolescent media use and mental health prior to and during COVID-19

This study examines associations between media use and mental health for adolescents prior to and during the COVID-19 pandemic.Using two separate datasets that sampled adolescents (8th, 10th, and 12th graders) in 2018 (n = 31,825) and 2020 (n = 1,523), mental health Stair Basket (hopelessness and happiness), media use (time spent using a variety of

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